Used in bone metabolism research to measure type I collagen degradation, providing insights into bone resorption activity. Commonly applied in studies of osteoporosis, metabolic bone diseases, and evaluation of anti-resorptive drug efficacy. Enables quantification of C-terminal telopeptide fragments in serum or urine samples, serving as a biomarker for assessing bone turnover in preclinical and clinical research. Widely utilized in pharmaceutical development and diagnostic laboratories for monitoring skeletal health and disease progression.