Used in immunology research to quantify levels of intercellular adhesion molecule-1 (ICAM-1) in biological samples such as serum, plasma, or cell culture supernatants. Helps assess inflammatory responses, as ICAM-1 is upregulated during inflammation and plays a role in leukocyte recruitment and immune cell adhesion. Commonly applied in studies of autoimmune diseases, infections, and endothelial activation. The ELISA format allows for sensitive and specific detection, enabling researchers to monitor disease progression or evaluate therapeutic interventions targeting inflammatory pathways.