Used in neuroscience research to quantify levels of neurofilament light chain (NFL) in cerebrospinal fluid (CSF) and blood samples. Helps assess axonal damage and neurodegeneration in conditions such as Alzheimer's disease, multiple sclerosis, amyotrophic lateral sclerosis (ALS), and traumatic brain injury. Enables monitoring of disease progression and response to therapeutic interventions in clinical and preclinical studies. Widely applied in biomarker discovery and validation due to its high sensitivity and specificity for neuronal injury.