Used in bioconjugation to link peptides, proteins, or drugs via amine-reactive chemistry, enhancing stability and solubility. Common in hydrogel formation for tissue engineering due to multi-armed structure enabling crosslinking. Applied in drug delivery systems to increase circulation time and reduce immunogenicity. Suitable for surface modification of biomaterials and nanoparticles. Also utilized in creating scaffolds for 3D cell culture and regenerative medicine.