Biotin-PEG8-OH is widely used in biochemical and bioconjugation applications due to its unique properties. The biotin moiety allows for strong and specific binding to avidin or streptavidin, making it valuable in affinity purification, immunoassays, and diagnostic assays. The PEG8 spacer enhances solubility and reduces steric hindrance, improving the efficiency of biotinylation reactions. It is commonly employed in the labeling of proteins, peptides, and other biomolecules for research in cell biology, molecular imaging, and drug delivery systems. Additionally, its hydrophilic nature makes it suitable for modifying surfaces or nanoparticles to enhance biocompatibility and targeting capabilities.