4'-Chloro-[1,1'-biphenyl]-4-carboxylic acid
95%
Reagent
Code: #162641
CAS Number
5748-41-4
blur_circular Chemical Specifications
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Molecular Information
Weight
232.66 g/mol
Formula
C₁₃H₉ClO₂
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Registry Numbers
MDL Number
MFCD03424592
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Physical Properties
Melting Point
289 - 291 ℃
Boiling Point
398.5 ℃ at 760 mmHg
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Storage & Handling
Density
1.298±0.06 g/cm3(Predicted)
Storage
Room temperature
description Product Description
Used as an intermediate in the synthesis of pharmaceuticals, particularly in the production of angiotensin II receptor antagonists like losartan and other sartan-class drugs for treating hypertension. It serves as a key building block due to its biphenyl structure with a carboxylic acid group, enabling coupling reactions in drug development. Also employed in the preparation of liquid crystals and organic electronic materials where substituted biphenyl motifs are required for desired physical and electronic properties. Its chloro substituent allows further functionalization, making it valuable in medicinal chemistry and materials science.
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