2-(5-chloro-2-methoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
98%
Reagent
Code: #161747
CAS Number
635305-45-2
blur_circular Chemical Specifications
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Molecular Information
Weight
268.54 g/mol
Formula
C₁₃H₁₈BClO₃
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Registry Numbers
MDL Number
MFCD22414441
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Storage & Handling
Storage
Room temperature
description Product Description
Used primarily as a key intermediate in Suzuki-Miyaura cross-coupling reactions, this compound enables the formation of carbon-carbon bonds in the synthesis of complex organic molecules. Its boronate ester group facilitates palladium-catalyzed coupling with aryl or vinyl halides, making it valuable in pharmaceutical and agrochemical research for constructing biaryl frameworks. It is especially useful in late-stage functionalization due to its stability and reactivity profile. Commonly employed in medicinal chemistry for lead optimization, it supports the efficient assembly of drug-like molecules containing chloro- and methoxy-substituted phenyl rings.
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