Tiludronate disodium hemihydrate is primarily used in veterinary medicine to treat bone disorders in horses, specifically navicular syndrome and other conditions involving abnormal bone remodeling. It works by inhibiting osteoclast activity, which helps reduce bone resorption and promotes a healthier bone structure. This treatment is administered via intravenous injection and is often part of a comprehensive management plan that includes rest and corrective shoeing. Its application ensures improved mobility and reduced pain in affected animals, enhancing their quality of life.