2-Chloro-1-(tetrahydro-2H-pyran-2-yl)-1H-imidazole-5-boronic acid pinacol ester
97%
Reagent
Code: #156604
CAS Number
1029684-36-3
blur_circular Chemical Specifications
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Molecular Information
Weight
312.6 g/mol
Formula
C₁₄H₂₂BClN₂O₃
thermostat
Physical Properties
Melting Point
135 °C
Boiling Point
466.0±55.0 °C(Predicted)
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Storage & Handling
Density
1.25±0.1 g/cm3(Predicted)
Storage
2-8°C
description Product Description
Used as a key intermediate in Suzuki-Miyaura cross-coupling reactions, enabling the synthesis of complex imidazole-containing compounds with high efficiency and selectivity. Its boronic ester group facilitates stable handling and improved reactivity in palladium-catalyzed couplings, making it valuable in pharmaceutical and agrochemical research for constructing biologically active molecules. The tetrahydropyranyl (THP) protecting group enhances solubility and stability during multi-step syntheses, particularly in the development of nitrogen-rich heterocyclic systems.
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