Trimethyl borate is widely used as a precursor in the synthesis of borate esters, which are essential in various industrial applications. It serves as a key reagent in the production of flame retardants, where it enhances the fire resistance of materials such as plastics, textiles, and wood. Additionally, it is utilized in the preparation of boron-containing polymers, which exhibit unique thermal and chemical stability.

In the field of organic synthesis, trimethyl borate acts as a methylating agent and is employed in the formation of boron-based intermediates. It also plays a significant role in the manufacture of specialty glasses and ceramics, where it contributes to improving their durability and resistance to thermal shock.

Furthermore, it is used as a solvent in certain chemical reactions and as a catalyst in esterification processes. Its application extends to the electronics industry, where it is involved in the production of semiconductors and other electronic components.