4,4,5,5-Tetramethyl-2-(2,3,6-trifluorophenyl)-1,3,2-dioxaborolane
95%
Reagent
Code: #130220
CAS Number
1819398-31-6
science Other reagents with same CAS 1819398-31-6
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Molecular Information
Weight
258.04 g/mol
Formula
C₁₂H₁₄BF₃O₂
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Registry Numbers
MDL Number
MFCD24039525
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Storage & Handling
Storage
2-8°C, sealed, dry
description Product Description
Used as a key reagent in Suzuki-Miyaura cross-coupling reactions, enabling the formation of carbon-carbon bonds in pharmaceutical and agrochemical synthesis. Its boron-containing structure acts as a coupling partner with aryl or vinyl halides in the presence of a palladium catalyst, facilitating the introduction of the 2,3,6-trifluorophenyl group into complex molecules. This makes it valuable in the development of fluorinated organic compounds, which often exhibit enhanced metabolic stability and bioavailability. Commonly employed in late-stage functionalization during drug discovery and in the preparation of advanced intermediates for materials science applications.
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