2,3-Difluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile

95%

Reagent Code: #130605
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CAS Number 2345641-33-8

science Other reagents with same CAS 2345641-33-8

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 265.06 g/mol
Formula C₁₃H₁₄BF₂NO₂
badge Registry Numbers
MDL Number MFCD31653750
thermostat Physical Properties
Boiling Point 345.1±42.0 °C(Predicted)
inventory_2 Storage & Handling
Density 1.18±0.1 g/cm3(Predicted)
Storage 2-8°C, Sealed, Inert Gas

description Product Description

Widely used in Suzuki-Miyaura cross-coupling reactions, this compound serves as a key intermediate in the synthesis of pharmaceuticals and agrochemicals. Its boronate ester group enables efficient carbon-carbon bond formation under mild conditions, making it valuable in medicinal chemistry for constructing biaryl structures. The presence of fluorine atoms enhances binding selectivity and metabolic stability in drug candidates. It is also employed in materials science for developing organic electronic materials due to its electron-withdrawing nitrile group and fluorinated aromatic core.

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Size Availability Unit Price Quantity
inventory 100mg
10-20 days ฿6,700.00
inventory 250mg
10-20 days ฿11,350.00

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2,3-Difluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile
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Widely used in Suzuki-Miyaura cross-coupling reactions, this compound serves as a key intermediate in the synthesis of pharmaceuticals and agrochemicals. Its boronate ester group enables efficient carbon-carbon bond formation under mild conditions, making it valuable in medicinal chemistry for constructing biaryl structures. The presence of fluorine atoms enhances binding selectivity and metabolic stability in drug candidates. It is also employed in materials science for developing organic electronic materials due to its electron-withdrawing nitrile group and fluorinated aromatic core.
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