1-(3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)cyclobutane-1-carboxylic acid
95%
Reagent
Code: #131605
CAS Number
2828447-06-7
science Other reagents with same CAS 2828447-06-7
blur_circular Chemical Specifications
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Molecular Information
Weight
302.18 g/mol
Formula
C₁₇H₂₃BO₄
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Registry Numbers
MDL Number
MFCD27936161
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Physical Properties
Boiling Point
460.9±38.0 °C(Predicted)
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Storage & Handling
Density
1.15±0.1 g/cm3(Predicted)
Storage
2-8°C, Sealed, Inert Gas
description Product Description
Used as a key intermediate in Suzuki-Miyaura cross-coupling reactions for the synthesis of complex organic molecules, particularly in pharmaceutical and agrochemical research. Its boronic ester group enables efficient carbon-carbon bond formation under mild conditions, making it valuable in drug discovery for building biaryl and heterobiaryl structures. The cyclobutane ring adds structural rigidity, which can enhance metabolic stability and influence the three-dimensional shape of target compounds. Commonly employed in late-stage functionalization due to its stability and reactivity profile.
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