tert-Butyl (2-((4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)sulfonamido)ethyl)carbamate
95%
science Other reagents with same CAS 1014613-14-9
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description Product Description
Used primarily as an intermediate in pharmaceutical synthesis, especially in the development of protease inhibitors and other bioactive molecules. Its structure contains both a sulfonamide group and a boronic ester, making it valuable in Suzuki-Miyaura cross-coupling reactions for constructing biaryl systems. The Boc-protected amine allows for selective deprotection and further functionalization in multi-step syntheses. Commonly employed in the preparation of enzyme inhibitors, including those targeting serine proteases, due to the ability of the boron-containing moiety to interact with active site residues. Also utilized in medicinal chemistry for the generation of analogs in structure-activity relationship studies.
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