tert-Butyl (2-((4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)sulfonamido)ethyl)carbamate

95%

Reagent Code: #131769
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CAS Number 1014613-14-9

science Other reagents with same CAS 1014613-14-9

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 426.34 g/mol
Formula C₁₉H₃₁BN₂O₆S
badge Registry Numbers
MDL Number MFCD28128481
inventory_2 Storage & Handling
Density 1.19±0.1 g/cm3(Predicted)
Storage 2-8°C, sealed, dry

description Product Description

Used primarily as an intermediate in pharmaceutical synthesis, especially in the development of protease inhibitors and other bioactive molecules. Its structure contains both a sulfonamide group and a boronic ester, making it valuable in Suzuki-Miyaura cross-coupling reactions for constructing biaryl systems. The Boc-protected amine allows for selective deprotection and further functionalization in multi-step syntheses. Commonly employed in the preparation of enzyme inhibitors, including those targeting serine proteases, due to the ability of the boron-containing moiety to interact with active site residues. Also utilized in medicinal chemistry for the generation of analogs in structure-activity relationship studies.

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Size Availability Unit Price Quantity
inventory 100mg
10-20 days ฿2,100.00
inventory 250mg
10-20 days ฿3,560.00
inventory 1g
10-20 days ฿9,600.00

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tert-Butyl (2-((4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)sulfonamido)ethyl)carbamate
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Used primarily as an intermediate in pharmaceutical synthesis, especially in the development of protease inhibitors and other bioactive molecules. Its structure contains both a sulfonamide group and a boronic ester, making it valuable in Suzuki-Miyaura cross-coupling reactions for constructing biaryl systems. The Boc-protected amine allows for selective deprotection and further functionalization in multi-step syntheses. Commonly employed in the preparation of enzyme inhibitors, including those targeting

Used primarily as an intermediate in pharmaceutical synthesis, especially in the development of protease inhibitors and other bioactive molecules. Its structure contains both a sulfonamide group and a boronic ester, making it valuable in Suzuki-Miyaura cross-coupling reactions for constructing biaryl systems. The Boc-protected amine allows for selective deprotection and further functionalization in multi-step syntheses. Commonly employed in the preparation of enzyme inhibitors, including those targeting serine proteases, due to the ability of the boron-containing moiety to interact with active site residues. Also utilized in medicinal chemistry for the generation of analogs in structure-activity relationship studies.

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