tert-Butyl 5-bromo-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole-1-carboxylate

95%

Reagent Code: #149029
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CAS Number 1024677-85-7

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 422.12 g/mol
Formula C₁₉H₂₅BBrNO₄
badge Registry Numbers
MDL Number MFCD12407263
inventory_2 Storage & Handling
Storage 2-8°C, dry

description Product Description

Widely used in cross-coupling reactions, this compound serves as a key intermediate in the synthesis of complex organic molecules, particularly in pharmaceutical and agrochemical industries. The presence of both bromo and boronate ester groups allows sequential functionalization through Suzuki-Miyaura coupling, enabling the construction of biaryl or heterobiaryl systems. It is especially valuable in the development of indole-based drug candidates, where selective modification of the indole core is required. The tert-butyloxycarbonyl (Boc) protecting group ensures nitrogen functionality remains intact during reactions, offering excellent chemoselectivity. Its stability and reactivity profile make it suitable for use in automated synthesis and library generation for drug discovery.

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Size Availability Unit Price Quantity
inventory 250mg
10-20 days ฿18,400.00
inventory 1g
10-20 days ฿37,600.00

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