(3-Bromo-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy)(tert-butyl)dimethylsilane
95%
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description Product Description
Used as an intermediate in organic synthesis, particularly in cross-coupling reactions such as Suzuki-Miyaura coupling. The boronate ester group at the 5-position enables formation of carbon-carbon bonds with aryl or vinyl halides, allowing construction of complex aromatic systems. The bromo substituent at the 3-position provides additional reactivity, enabling selective cross-coupling or serving as a handle for further derivatization. The silyl ether group acts as a protected phenol, which can be deprotected under mild acidic or basic conditions to release the free phenol when needed. This dual functionality, combined with the bromo group, makes it valuable in multi-step synthesis of pharmaceuticals, agrochemicals, and functional materials where selective reactivity and protection strategies are required. Its stability and selective reactivity profile support use in late-stage functionalization and parallel synthesis in drug discovery.
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