(3-Bromo-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy)(tert-butyl)dimethylsilane

95%

Reagent Code: #152291
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CAS Number 1218789-51-5

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 413.23 g/mol
Formula C₁₈H₃₀BBrO₃Si
badge Registry Numbers
MDL Number MFCD12546591
inventory_2 Storage & Handling
Storage Room temperature

description Product Description

Used as an intermediate in organic synthesis, particularly in cross-coupling reactions such as Suzuki-Miyaura coupling. The boronate ester group at the 5-position enables formation of carbon-carbon bonds with aryl or vinyl halides, allowing construction of complex aromatic systems. The bromo substituent at the 3-position provides additional reactivity, enabling selective cross-coupling or serving as a handle for further derivatization. The silyl ether group acts as a protected phenol, which can be deprotected under mild acidic or basic conditions to release the free phenol when needed. This dual functionality, combined with the bromo group, makes it valuable in multi-step synthesis of pharmaceuticals, agrochemicals, and functional materials where selective reactivity and protection strategies are required. Its stability and selective reactivity profile support use in late-stage functionalization and parallel synthesis in drug discovery.

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Size Availability Unit Price Quantity
inventory 100mg
10-20 days ฿960.00
inventory 250mg
10-20 days ฿1,590.00
inventory 1g
10-20 days ฿4,270.00
inventory 5g
10-20 days ฿14,910.00

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