tert-Butyldimethyl(1-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)cyclopropoxy)silane
95%
Reagent
Code: #155344
CAS Number
2172379-68-7
blur_circular Chemical Specifications
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Molecular Information
Weight
374.40 g/mol
Formula
C₂₁H₃₅BO₃Si
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Storage & Handling
Storage
Room temperature
description Product Description
Used as a key intermediate in Suzuki-Miyaura cross-coupling reactions, enabling the formation of carbon-carbon bonds in complex organic synthesis. Its boronate ester group participates in palladium-catalyzed couplings with aryl or vinyl halides, making it valuable in pharmaceutical and agrochemical research for constructing biaryl and styrene derivatives. The tert-butyldimethylsilyl (TBS) protected cyclopropoxy group provides stability during reaction sequences and can be selectively deprotected to release the alcohol functionality when needed. This dual functionality allows for stepwise, controlled synthesis in multi-step routes, particularly in the development of bioactive molecules.
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