2-Chloro-5-(trifluoromethyl)phenylboronic acid pinacol ester
98%
Reagent
Code: #161742
CAS Number
1146214-95-0
blur_circular Chemical Specifications
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Molecular Information
Weight
306.5162096 g/mol
Formula
C₁₃H₁₅BClF₃O₂
thermostat
Physical Properties
Boiling Point
326.4±42.0℃(Predicted)
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Storage & Handling
Density
1.23±0.1g/ml(Predicted)
Storage
2-8℃, dry, sealed
description Product Description
Widely used in Suzuki-Miyaura cross-coupling reactions, this compound serves as a key building block for constructing carbon-carbon bonds in pharmaceutical and agrochemical synthesis. Its boronic ester group offers enhanced stability and reactivity, making it ideal for introducing chloro- and trifluoromethyl-substituted aryl moieties into complex molecules. It is particularly valuable in the development of bioactive compounds where the trifluoromethyl group improves metabolic stability and lipophilicity. Commonly employed in late-stage functionalization, it enables efficient diversification of aromatic scaffolds in drug discovery and materials science.
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