2-(2,6-Difluoro-4-methylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

95%

Reagent Code: #167199
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CAS Number 1355011-22-1

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 254.08 g/mol
Formula C₁₃H₁₇F₂O₂B
badge Registry Numbers
MDL Number MFCD22418271
thermostat Physical Properties
Boiling Point 298.8±40.0 °C(Predicted)
inventory_2 Storage & Handling
Density 1.10±0.1 g/cm3(Predicted)
Storage Room temperature, inert gas

description Product Description

Used as a key intermediate in Suzuki-Miyaura cross-coupling reactions, enabling the formation of carbon-carbon bonds in pharmaceutical and agrochemical synthesis. Its boronate ester group facilitates efficient coupling with aryl halides under mild conditions, making it valuable in the preparation of complex organic molecules, particularly in drug discovery and development. The difluoro substitution enhances metabolic stability and binding affinity in bioactive compounds, while the methyl group aids in tuning electronic and steric properties. Commonly employed in late-stage functionalization to introduce aromatic fragments in medicinal chemistry campaigns.

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Size Availability Unit Price Quantity
inventory 100mg
10-20 days ฿5,490.00
inventory 5g
10-20 days ฿84,700.00
inventory 1g
10-20 days ฿24,210.00

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