2-(2,2-difluoro-1-phenylcyclopropyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
95%
Reagent
Code: #176335
CAS Number
1010689-64-1
blur_circular Chemical Specifications
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Molecular Information
Weight
280.14 g/mol
Formula
C₁₅H₁₉BF₂O₂
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Storage & Handling
Storage
2-8℃
description Product Description
Used as a key reagent in Suzuki-Miyaura cross-coupling reactions, enabling the formation of carbon-carbon bonds in the synthesis of complex organic molecules. Its boronate ester group facilitates efficient and selective coupling with aryl or vinyl halides under palladium catalysis. Commonly applied in pharmaceutical and agrochemical research for constructing biaryl frameworks and functionalized cyclopropane derivatives. The difluorocyclopropyl moiety enhances metabolic stability and lipophilicity, making it valuable in medicinal chemistry for drug design. Stable and compatible with a range of functional groups, it supports late-stage functionalization in multistep syntheses.
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