2-((4,4-difluorocyclohexylidene)methyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
98%
Reagent
Code: #176380
CAS Number
2246650-11-1
blur_circular Chemical Specifications
scatter_plot
Molecular Information
Weight
258.12 g/mol
Formula
C₁₃H₂₁BF₂O₂
inventory_2
Storage & Handling
Storage
2-8℃
description Product Description
Used as a key intermediate in Suzuki-Miyaura cross-coupling reactions, enabling the introduction of difluorocyclohexyl groups into aromatic and heteroaromatic systems. Its boronate ester functionality allows for efficient carbon-carbon bond formation under mild conditions, making it valuable in medicinal chemistry for constructing fluorinated analogs of drug candidates. The presence of geminal difluorides enhances metabolic stability and membrane permeability in bioactive molecules, supporting its use in the development of pharmaceuticals and agrochemicals. Commonly employed in late-stage functionalization to explore structure-activity relationships in lead optimization.
shopping_cart Available Sizes & Pricing
Cart
No products
Subtotal:
0.00
Total
0.00
THB