2-((4,4-difluorocyclohexylidene)methyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

98%

Reagent Code: #176380
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CAS Number 2246650-11-1

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 258.12 g/mol
Formula C₁₃H₂₁BF₂O₂
inventory_2 Storage & Handling
Storage 2-8℃

description Product Description

Used as a key intermediate in Suzuki-Miyaura cross-coupling reactions, enabling the introduction of difluorocyclohexyl groups into aromatic and heteroaromatic systems. Its boronate ester functionality allows for efficient carbon-carbon bond formation under mild conditions, making it valuable in medicinal chemistry for constructing fluorinated analogs of drug candidates. The presence of geminal difluorides enhances metabolic stability and membrane permeability in bioactive molecules, supporting its use in the development of pharmaceuticals and agrochemicals. Commonly employed in late-stage functionalization to explore structure-activity relationships in lead optimization.

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Size Availability Unit Price Quantity
inventory 100mg
10-20 days ฿5,310.00
inventory 5g
10-20 days ฿65,250.00
inventory bulk
10-20 days ฿0.00
inventory 1g
10-20 days ฿27,450.00

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