2-Amino-4-(iso-propyl)pyrimidine-5-boronic acid pinacol ester
95%
Reagent
Code: #89713
CAS Number
2223041-79-8
blur_circular Chemical Specifications
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Molecular Information
Weight
281.15896 g/mol
Formula
C₁₃H₂₄BN₃O₃
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Storage & Handling
Storage
-20°C, sealed, dry
description Product Description
Primarily utilized in organic synthesis, this compound serves as a key intermediate in the preparation of complex molecules, particularly in the pharmaceutical industry. Its boronic ester functionality enables participation in Suzuki-Miyaura cross-coupling reactions, a widely employed method for forming carbon-carbon bonds. This reaction is crucial for constructing biaryl structures, which are common motifs in many drugs and bioactive compounds. Additionally, the pyrimidine core of the molecule makes it valuable in the development of nucleoside analogs, which are often explored for antiviral and anticancer applications. Its isopropyl group can influence the steric and electronic properties, aiding in the fine-tuning of drug candidates for improved efficacy and selectivity.
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