1-(4-fluorophenyl)-3-(3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)urea
95%
Reagent
Code: #89988
CAS Number
874301-65-2
blur_circular Chemical Specifications
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Molecular Information
Weight
356.2 g/mol
Formula
C₁₉H₂₂BFN₂O₃
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Registry Numbers
MDL Number
MFCD22494545
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Storage & Handling
Storage
2-8°C
description Product Description
This compound is primarily utilized in the field of medicinal chemistry and drug development, particularly as an intermediate in the synthesis of biologically active molecules. Its structure, featuring a urea moiety and a boronate ester group, makes it valuable for constructing compounds with potential therapeutic applications. The boronate ester group is often employed in Suzuki-Miyaura cross-coupling reactions, a key method for forming carbon-carbon bonds in the synthesis of complex organic molecules, including pharmaceuticals. Additionally, the presence of the fluorophenyl group can enhance the metabolic stability and binding affinity of the resulting compounds, making it useful in the design of drugs targeting specific proteins or enzymes. Its applications are particularly relevant in the development of kinase inhibitors, which are important in cancer therapy and other disease treatments.
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