1-Isobutyl-3-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)urea
95%
Reagent
Code: #90408
CAS Number
874291-03-9
blur_circular Chemical Specifications
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Molecular Information
Weight
318.2189 g/mol
Formula
C₁₇H₂₇BN₂O₃
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Registry Numbers
MDL Number
MFCD09027289
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Physical Properties
Boiling Point
415.1 °C at 760 mmHg
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Storage & Handling
Density
1.06 g/cm3
Storage
2-8°C
description Product Description
This compound is primarily used in the field of medicinal chemistry and drug development. It serves as a key intermediate in the synthesis of biologically active molecules, particularly those targeting enzyme inhibition or receptor modulation. Its boronate ester functionality makes it valuable in Suzuki-Miyaura cross-coupling reactions, a widely used method for constructing carbon-carbon bonds in pharmaceutical research. Additionally, it is employed in the development of proteolysis-targeting chimeras (PROTACs), which are innovative therapeutic agents designed to degrade specific disease-causing proteins. Its structural features also make it suitable for use in the preparation of boron-containing compounds, which are increasingly explored for their potential in cancer therapy and imaging applications.
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1-Isobutyl-3-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)urea
This compound is primarily used in the field of medicinal chemistry and drug development. It serves as a key intermediate in the synthesis of biologically active molecules, particularly those targeting enzyme inhibition or receptor modulation. Its boronate ester functionality makes it valuable in Suzuki-Miyaura cross-coupling reactions, a widely used method for constructing carbon-carbon bonds in pharmaceutical research. Additionally, it is employed in the development of proteolysis-targeting chimeras (PROTACs), which are innovative therapeutic agents designed to degrade specific disease-causing proteins. Its structural features also make it suitable for use in the preparation of boron-containing compounds, which are increasingly explored for their potential in cancer therapy and imaging applications.
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