(2-(2,2,2-Trifluoroethoxy)pyrimidin-5-yl)boronic acid

98%

Reagent Code: #130362
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CAS Number 1401163-85-6

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 221.93 g/mol
Formula C₆H₆BF₃N₂O₃
badge Registry Numbers
MDL Number MFCD07375137
thermostat Physical Properties
Boiling Point 348.4±52.0 °C(Predicted)
inventory_2 Storage & Handling
Density 1.50±0.1 g/cm3(Predicted)
Storage 2-8°C, Sealed, Inert Gas

description Product Description

Used as a key intermediate in Suzuki-Miyaura cross-coupling reactions for the synthesis of biologically active compounds, particularly in pharmaceutical and agrochemical research. Its boronic acid functionality enables efficient carbon-carbon bond formation with aryl or heteroaryl halides, making it valuable in constructing complex molecules. The presence of a trifluoroethoxy group enhances metabolic stability and lipophilicity, which is beneficial in drug design, especially for targeting enzymes or receptors in medicinal chemistry programs. Commonly employed in the development of kinase inhibitors and other therapeutic agents where fluorinated heterocycles improve pharmacokinetic properties.

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Size Availability Unit Price Quantity
inventory 250mg
10-20 days ฿4,990.00
inventory 1g
10-20 days ฿13,300.00

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