(2-(2,2,2-Trifluoroethoxy)pyrimidin-5-yl)boronic acid
98%
Reagent
Code: #130362
CAS Number
1401163-85-6
blur_circular Chemical Specifications
scatter_plot
Molecular Information
Weight
221.93 g/mol
Formula
C₆H₆BF₃N₂O₃
badge
Registry Numbers
MDL Number
MFCD07375137
thermostat
Physical Properties
Boiling Point
348.4±52.0 °C(Predicted)
inventory_2
Storage & Handling
Density
1.50±0.1 g/cm3(Predicted)
Storage
2-8°C, Sealed, Inert Gas
description Product Description
Used as a key intermediate in Suzuki-Miyaura cross-coupling reactions for the synthesis of biologically active compounds, particularly in pharmaceutical and agrochemical research. Its boronic acid functionality enables efficient carbon-carbon bond formation with aryl or heteroaryl halides, making it valuable in constructing complex molecules. The presence of a trifluoroethoxy group enhances metabolic stability and lipophilicity, which is beneficial in drug design, especially for targeting enzymes or receptors in medicinal chemistry programs. Commonly employed in the development of kinase inhibitors and other therapeutic agents where fluorinated heterocycles improve pharmacokinetic properties.
shopping_cart Available Sizes & Pricing
Cart
No products
Subtotal:
0.00
Total
0.00
THB