(4-((4-(Trifluoromethoxy)phenoxy)methyl)phenyl)boronic acid

98%

Reagent Code: #131923
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CAS Number 870778-97-5

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 312.05 g/mol
Formula C₁₄H₁₂BF₃O₄
badge Registry Numbers
MDL Number MFCD08276770
thermostat Physical Properties
Boiling Point 415.5±55.0 °C(Predicted)
inventory_2 Storage & Handling
Density 1.37±0.1 g/cm3(Predicted)
Storage Room temperature, seal, inert gas

description Product Description

Used in organic synthesis as a building block for Suzuki-Miyaura cross-coupling reactions, enabling the formation of biaryl compounds important in pharmaceutical and agrochemical development. Its boronic acid group on a phenyl ring substituted with a ((4-(trifluoromethoxy)phenoxy)methyl) moiety facilitates carbon-carbon bond formation under mild conditions. The trifluoromethoxy substituent enhances lipophilicity, metabolic stability, and biological activity, while the phenoxymethyl ether linkage contributes to improved solubility and absorption properties, making it valuable in drug discovery for constructing complex aromatic structures with optimized pharmacokinetic profiles. Commonly employed in the preparation of intermediates for bioactive molecules, including potential therapeutics targeting inflammation, cancer, and central nervous system disorders. Also utilized in materials science for designing organic electronic materials due to its stability and reactivity profile.

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Size Availability Unit Price Quantity
inventory 250mg
10-20 days ฿3,140.00
inventory 1g
10-20 days ฿10,620.00
inventory 5g
10-20 days ฿40,640.00

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