4-Fluoro-2-(trifluoromethyl)benzeneboronic acid
98%
Reagent
Code: #90591
Alias
4-Fluoro-2-trifluoromethylphenylboronic acid
CAS Number
182344-16-7
blur_circular Chemical Specifications
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Molecular Information
Weight
207.92 g/mol
Formula
C₇H₅BF₄O₂
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Registry Numbers
MDL Number
MFCD08062379
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Physical Properties
Melting Point
183-186°C
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Storage & Handling
Storage
room temperature
description Product Description
This chemical is widely used in organic synthesis, particularly in Suzuki-Miyaura cross-coupling reactions. It serves as a key intermediate for the construction of complex aromatic compounds, which are essential in the development of pharmaceuticals, agrochemicals, and advanced materials. Its boronic acid group facilitates the formation of carbon-carbon bonds, enabling the synthesis of biaryl structures that are often found in active pharmaceutical ingredients (APIs). Additionally, it is employed in the preparation of fluorinated organic compounds, which are valuable in medicinal chemistry due to their enhanced metabolic stability and bioavailability. The compound’s trifluoromethyl group further contributes to its utility in creating molecules with unique electronic and steric properties, making it a versatile tool in drug discovery and material science.
format_list_bulleted Product Specification
Test Parameter | Specification |
---|---|
Melting point | 183-186 |
Purity (HPLC) | 98-100% |
Appearance | White to off-white powder or solid or chunks |
Infrared Spectrometry | Conforms to Structure |
Proton NMR Spectrum | Conforms to Structure |
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4-Fluoro-2-(trifluoromethyl)benzeneboronic acid
This chemical is widely used in organic synthesis, particularly in Suzuki-Miyaura cross-coupling reactions. It serves as a key intermediate for the construction of complex aromatic compounds, which are essential in the development of pharmaceuticals, agrochemicals, and advanced materials. Its boronic acid group facilitates the formation of carbon-carbon bonds, enabling the synthesis of biaryl structures that are often found in active pharmaceutical ingredients (APIs). Additionally, it is employed in the preparation of fluorinated organic compounds, which are valuable in medicinal chemistry due to their enhanced metabolic stability and bioavailability. The compound’s trifluoromethyl group further contributes to its utility in creating molecules with unique electronic and steric properties, making it a versatile tool in drug discovery and material science.
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