4-Fluoro-2-(trifluoromethyl)benzeneboronic acid

98%

Reagent Code: #90591
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Alias 4-Fluoro-2-trifluoromethylphenylboronic acid
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CAS Number 182344-16-7

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 207.92 g/mol
Formula C₇H₅BF₄O₂
badge Registry Numbers
MDL Number MFCD08062379
thermostat Physical Properties
Melting Point 183-186°C
inventory_2 Storage & Handling
Storage room temperature

description Product Description

This chemical is widely used in organic synthesis, particularly in Suzuki-Miyaura cross-coupling reactions. It serves as a key intermediate for the construction of complex aromatic compounds, which are essential in the development of pharmaceuticals, agrochemicals, and advanced materials. Its boronic acid group facilitates the formation of carbon-carbon bonds, enabling the synthesis of biaryl structures that are often found in active pharmaceutical ingredients (APIs). Additionally, it is employed in the preparation of fluorinated organic compounds, which are valuable in medicinal chemistry due to their enhanced metabolic stability and bioavailability. The compound’s trifluoromethyl group further contributes to its utility in creating molecules with unique electronic and steric properties, making it a versatile tool in drug discovery and material science.

format_list_bulleted Product Specification

Test Parameter Specification
Melting point 183-186
Purity (HPLC) 98-100%
Appearance White to off-white powder or solid or chunks
Infrared Spectrometry Conforms to Structure
Proton NMR Spectrum Conforms to Structure

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 250mg
10-20 days ฿330.00
inventory 1g
10-20 days ฿410.00
inventory 5g
10-20 days ฿1,300.00
inventory 25g
10-20 days ฿5,330.00
4-Fluoro-2-(trifluoromethyl)benzeneboronic acid
This chemical is widely used in organic synthesis, particularly in Suzuki-Miyaura cross-coupling reactions. It serves as a key intermediate for the construction of complex aromatic compounds, which are essential in the development of pharmaceuticals, agrochemicals, and advanced materials. Its boronic acid group facilitates the formation of carbon-carbon bonds, enabling the synthesis of biaryl structures that are often found in active pharmaceutical ingredients (APIs). Additionally, it is employed in the preparation of fluorinated organic compounds, which are valuable in medicinal chemistry due to their enhanced metabolic stability and bioavailability. The compound’s trifluoromethyl group further contributes to its utility in creating molecules with unique electronic and steric properties, making it a versatile tool in drug discovery and material science.
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