4-(Benzyloxy)-2-fluorophenylboronic acid

96%

Reagent Code: #90729
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Alias 4-Benzyloxy-2-fluorophenylboronic acid
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CAS Number 166744-78-1

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 246.04 g/mol
Formula C₁₃H₁₂BFO₃
badge Registry Numbers
MDL Number MFCD02093064
thermostat Physical Properties
Melting Point 151 °C
inventory_2 Storage & Handling
Storage 2~8°C

description Product Description

4-(Benzyloxy)-2-fluorophenylboronic acid is primarily utilized in organic synthesis, particularly in Suzuki-Miyaura cross-coupling reactions. This reaction is widely employed to form carbon-carbon bonds, making it valuable in the production of pharmaceuticals, agrochemicals, and advanced materials. Its boronic acid group acts as a key functional moiety, enabling the coupling with aryl or vinyl halides in the presence of a palladium catalyst. Additionally, it can be used in the development of bioactive compounds, where the fluorine atom enhances metabolic stability and binding affinity. Its benzyloxy group also provides a protective function during multi-step synthetic processes, allowing for selective deprotection when needed.

format_list_bulleted Product Specification

Test Parameter Specification
Purity (HPLC) 96-100
Melting Point (°C) 151-155
Infrared Spectrum Conforms to structure
Proton NMR Spectrum Conforms to structure

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 250mg
10-20 days ฿1,008.00
inventory 1g
10-20 days ฿2,304.00
inventory 5g
10-20 days ฿9,180.00
4-(Benzyloxy)-2-fluorophenylboronic acid
4-(Benzyloxy)-2-fluorophenylboronic acid is primarily utilized in organic synthesis, particularly in Suzuki-Miyaura cross-coupling reactions. This reaction is widely employed to form carbon-carbon bonds, making it valuable in the production of pharmaceuticals, agrochemicals, and advanced materials. Its boronic acid group acts as a key functional moiety, enabling the coupling with aryl or vinyl halides in the presence of a palladium catalyst. Additionally, it can be used in the development of bioactive compounds, where the fluorine atom enhances metabolic stability and binding affinity. Its benzyloxy group also provides a protective function during multi-step synthetic processes, allowing for selective deprotection when needed.
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