4-(Benzyloxy)-2-fluorophenylboronic acid
96%
Reagent
Code: #90729
Alias
4-Benzyloxy-2-fluorophenylboronic acid
CAS Number
166744-78-1
blur_circular Chemical Specifications
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Molecular Information
Weight
246.04 g/mol
Formula
C₁₃H₁₂BFO₃
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Registry Numbers
MDL Number
MFCD02093064
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Physical Properties
Melting Point
151 °C
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Storage & Handling
Storage
2~8°C
description Product Description
4-(Benzyloxy)-2-fluorophenylboronic acid is primarily utilized in organic synthesis, particularly in Suzuki-Miyaura cross-coupling reactions. This reaction is widely employed to form carbon-carbon bonds, making it valuable in the production of pharmaceuticals, agrochemicals, and advanced materials. Its boronic acid group acts as a key functional moiety, enabling the coupling with aryl or vinyl halides in the presence of a palladium catalyst. Additionally, it can be used in the development of bioactive compounds, where the fluorine atom enhances metabolic stability and binding affinity. Its benzyloxy group also provides a protective function during multi-step synthetic processes, allowing for selective deprotection when needed.
format_list_bulleted Product Specification
Test Parameter | Specification |
---|---|
Purity (HPLC) | 96-100 |
Melting Point (°C) | 151-155 |
Infrared Spectrum | Conforms to structure |
Proton NMR Spectrum | Conforms to structure |
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4-(Benzyloxy)-2-fluorophenylboronic acid
4-(Benzyloxy)-2-fluorophenylboronic acid is primarily utilized in organic synthesis, particularly in Suzuki-Miyaura cross-coupling reactions. This reaction is widely employed to form carbon-carbon bonds, making it valuable in the production of pharmaceuticals, agrochemicals, and advanced materials. Its boronic acid group acts as a key functional moiety, enabling the coupling with aryl or vinyl halides in the presence of a palladium catalyst. Additionally, it can be used in the development of bioactive compounds, where the fluorine atom enhances metabolic stability and binding affinity. Its benzyloxy group also provides a protective function during multi-step synthetic processes, allowing for selective deprotection when needed.
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