[2-(n-Propoxy)-4-methyl-d10]-pyrimidine-5-boronic acid
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Used primarily in organic synthesis, this deuterated compound ([2-(n-Propoxy)-4-methyl-d10]-pyrimidine-5-boronic acid) serves as a key intermediate in the preparation of complex molecules, particularly in pharmaceutical research. It is often employed in Suzuki-Miyaura cross-coupling reactions, a widely used method for forming carbon-carbon bonds. This enables the construction of diverse aromatic and heteroaromatic structures, which are essential in developing drug candidates. Its boronic acid group facilitates efficient coupling with various halides, making it valuable in creating biologically active compounds. The deuteration (d10) at the 4-methyl position is particularly useful in studies involving isotopic labeling, aiding in metabolic, pharmacokinetic, and mechanistic research by allowing NMR and mass spectrometry tracking without altering the molecule's reactivity.
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