Used as a key intermediate in the synthesis of biologically active compounds, particularly in pharmaceuticals targeting central nervous system disorders. Its rigid bicyclic structure and functional groups make it valuable for designing enzyme inhibitors and receptor modulators. The cyano and carboxylate groups allow further chemical modifications, enabling the development of analogs for structure-activity relationship studies. Commonly employed in the preparation of potent neurokinin antagonists and other therapeutic agents requiring high selectivity and metabolic stability.