mPEG12-Br is widely used in the field of polymer chemistry and bioconjugation. It serves as a crucial reagent for modifying biomolecules, such as proteins, peptides, and nucleic acids, to enhance their solubility, stability, and bioavailability. The bromine group allows for efficient functionalization through nucleophilic substitution reactions, making it a valuable tool for creating PEGylated compounds. These PEGylated products are often employed in drug delivery systems to improve pharmacokinetics and reduce immunogenicity. Additionally, mPEG12-Br is utilized in the synthesis of advanced materials, including hydrogels and nanoparticles, for applications in tissue engineering and targeted therapy. Its versatility and reactivity make it a key component in developing innovative biomedical and pharmaceutical solutions.