Used primarily in the treatment of hypertension (high blood pressure), pranidipine is a calcium channel blocker that helps relax blood vessels, improving blood flow and reducing the workload on the heart. It is particularly effective in managing essential hypertension and may offer additional benefits in patients with renal impairment due to its vasodilatory effects on renal arteries. Its long-acting profile allows for once-daily dosing, enhancing patient compliance. Pranidipine is also studied for potential protective effects on vascular endothelium, suggesting a role beyond blood pressure control in cardiovascular risk reduction.