WT IDH1 Inhibitor 2
≥98%
Reagent
Code: #109943
CAS Number
1816272-19-1
blur_circular Chemical Specifications
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Molecular Information
Weight
501.55 g/mol
Formula
C₂₈H₂₈FN₅O₃
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Storage & Handling
Storage
-20°C, dry, sealed
description Product Description
This compound is primarily used in the field of cancer research and therapy, specifically targeting cancers associated with mutations in the IDH1 gene. It functions as an inhibitor of the mutant IDH1 enzyme, which is known to produce an oncometabolite, 2-hydroxyglutarate, that drives tumor growth. By inhibiting this enzyme, the compound helps to normalize cellular metabolism and reduce tumor progression. It is particularly relevant in the treatment of certain types of gliomas and acute myeloid leukemia (AML), where IDH1 mutations are prevalent. Research and clinical studies focus on its potential to improve patient outcomes by selectively targeting cancer cells while sparing healthy tissues.
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