Used in cancer research, particularly for studying tumor growth and metastasis in lung, colon, and breast cancers. Supports development of targeted therapies and antibody-drug conjugates due to its overexpression in malignant cells. Employed in flow cytometry and immunofluorescence assays to validate antibody specificity. Serves as a functional model for investigating cell proliferation, migration, and signaling pathways linked to oncogenesis. Also utilized in high-throughput screening for anti-cancer compounds and therapeutic antibodies.