AM-2394 is primarily utilized in research settings, particularly in the study of cannabinoid receptors and their interactions. It serves as a potent agonist for the CB1 receptor, making it valuable for investigating the endocannabinoid system and its physiological effects. Researchers use it to explore potential therapeutic applications, such as pain management, appetite regulation, and neuroprotection. Its strong binding affinity also aids in understanding receptor signaling pathways and the development of targeted cannabinoid-based therapies. However, due to its potency, it is strictly confined to laboratory use and not approved for medical or recreational purposes.