AM679 is primarily used in research settings to study the endocannabinoid system, particularly as a potent and selective agonist for the cannabinoid receptor CB1. Its application is significant in understanding the physiological and pathological roles of CB1 receptors in the central nervous system and peripheral tissues. Researchers utilize AM679 to explore its effects on neurotransmitter release, neuronal excitability, and synaptic plasticity, which are critical in conditions like pain, inflammation, and neurological disorders. Additionally, it serves as a tool compound in drug discovery efforts aimed at developing therapeutic agents targeting the endocannabinoid system for diseases such as epilepsy, anxiety, and chronic pain. Its high selectivity and potency make it valuable for mechanistic studies and preclinical investigations.