CORM-3 is widely used in biomedical research due to its ability to release carbon monoxide (CO) in controlled amounts. This property makes it valuable in studying the therapeutic effects of CO, which include anti-inflammatory, anti-apoptotic, and vasodilatory actions. It is often applied in experimental models to protect against ischemia-reperfusion injury, reduce inflammation in conditions like arthritis, and improve outcomes in organ transplantation. Additionally, CORM-3 is utilized in cancer research to explore its potential in inducing cancer cell death while sparing healthy cells. Its applications extend to studying cardiovascular diseases, where it helps in understanding CO's role in regulating blood pressure and vascular function.