CORM-A1 is widely used in biomedical research due to its ability to release carbon monoxide (CO) in a controlled manner. This property makes it valuable in studying the therapeutic effects of CO, which has been shown to exhibit anti-inflammatory, anti-apoptotic, and vasodilatory properties. It is particularly utilized in experimental models to protect against ischemia-reperfusion injury, a common complication in organ transplantation and cardiovascular diseases. Additionally, CORM-A1 is employed in research focused on mitigating inflammation in conditions such as sepsis, arthritis, and lung injury. Its controlled CO release mechanism allows for precise dosing, making it a useful tool in understanding the signaling pathways and potential therapeutic applications of CO in various diseases.