4-(2-Bromoacetyl)benzene-1-sulfonamide
95%
Reagent
Code: #153728
CAS Number
944-33-2
blur_circular Chemical Specifications
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Molecular Information
Weight
278.123 g/mol
Formula
C₈H₈BrNO₃S
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Registry Numbers
MDL Number
MFCD08689427
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Storage & Handling
Storage
2-8°C, Inert Gas
description Product Description
Used as an intermediate in the synthesis of sulfa drugs, particularly in the development of antibacterial agents. Its reactive bromoacetyl group allows for easy conjugation with nucleophiles, making it valuable in medicinal chemistry for building more complex sulfonamide derivatives. Commonly employed in the preparation of enzyme inhibitors, especially carbonic anhydrase inhibitors, due to the strong affinity of sulfonamides for zinc-containing active sites. Also utilized in biochemical research for labeling or modifying proteins and peptides through covalent attachment. Its structural features support use in creating targeted pharmaceuticals with enhanced binding and selectivity.
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