14β,16β-Dihydroxy-3β-(β-D-glucopyranosyloxy)-5α-bufa-20,22-dienolide
98%
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description Product Description
Used in pharmaceutical research for its potential cardiotonic properties, particularly in the development of heart failure treatments. Shows activity in modulating cardiac muscle contraction through interaction with ion transport systems, such as Na⁺/K⁺-ATPase. Investigated for its influence on myocardial cell signaling and as a lead compound in synthesizing derivatives with improved bioavailability and reduced toxicity. Also explored for anti-arrhythmic effects and in studies of glycoside-receptor interactions in cardiovascular tissues.
Additionally, the glycoside structure with glucose enhances water solubility, potentially improving absorption and efficacy compared to non-glycosylated analogs, making it suitable for intravenous or injectable formulations.
Some studies suggest potential anti-inflammatory and anti-cancer effects at the cellular level, though these are still in preliminary in vitro and animal testing stages and not yet widely used in clinical settings.
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