Used primarily as an antiproliferative agent in drug-eluting stents to prevent restenosis after angioplasty. It inhibits smooth muscle cell proliferation and migration, reducing the risk of re-narrowing of arteries. Its immunosuppressive properties also make it suitable for coating cardiovascular implants, where it is slowly released to exert localized therapeutic effects without significant systemic exposure. Research explores its potential in other medical devices and coatings for controlled drug delivery.