Palosuran is primarily used in medical research as a selective antagonist for the urotensin-II receptor. It plays a significant role in studying cardiovascular diseases, particularly hypertension and heart failure, by blocking the effects of urotensin-II, a potent vasoconstrictor. Researchers utilize Palosuran to investigate its potential therapeutic effects in managing conditions related to abnormal blood vessel constriction and kidney function. Its application extends to exploring pathways involved in fibrosis and inflammation, offering insights into novel treatment strategies for related disorders.