Used in research settings as a selective inhibitor of CDK8 (Cyclin-Dependent Kinase 8), helping to study the role of CDK8 in transcription regulation and its involvement in cancer pathways. Shows potential in oncology research, particularly in leukemia and colorectal cancer models, where CDK8 activity is linked to disease progression. Also employed to investigate inflammatory signaling and immune responses due to CDK8's role in modulating gene expression related to inflammation.