3-amino-6-pyridin-4-yl-N-(3,4,5-trimethoxyphenyl)thieno[2,3-b]pyridine-2-carboxamide
98%
Reagent
Code: #245790
CAS Number
445267-51-6
science Other reagents with same CAS 445267-51-6
blur_circular Chemical Specifications
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Molecular Information
Weight
436.48 g/mol
Formula
C₂₂H₂₀N₄O₄S
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Registry Numbers
MDL Number
MFCD03075754
thermostat
Physical Properties
Boiling Point
592.9±50.0 °C(Predicted)
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Storage & Handling
Density
1.372±0.06 g/cm3(Predicted)
Storage
-20°C, away from light, dry
description Product Description
Used in pharmaceutical research as a kinase inhibitor, particularly showing activity against cyclin-dependent kinases (CDKs). It has been investigated for its potential in cancer therapy due to its ability to interfere with cell cycle progression and induce apoptosis in tumor cells. Its structure allows for strong binding to ATP sites in kinases, making it a lead compound in developing antiproliferative agents. Also explored for use in combination therapies to overcome drug resistance in solid tumors.