AMG 925 HCl is primarily used in research settings as a potent and selective inhibitor of FLT3 and CDK4 kinases. Its application is significant in the study of cancer biology, particularly in understanding the mechanisms of cell cycle regulation and proliferation in malignancies such as acute myeloid leukemia (AML). Researchers utilize this compound to investigate the therapeutic potential of targeting FLT3 and CDK4 pathways, which are often dysregulated in various cancers. Additionally, AMG 925 HCl serves as a valuable tool in preclinical studies to evaluate the efficacy of kinase inhibitors in reducing tumor growth and improving survival outcomes. Its role in drug development and cancer research underscores its importance in advancing targeted cancer therapies.