Arg-Phe-Asp-Ser is a tetrapeptide that finds application in biochemical research, particularly in the study of cell adhesion and signaling pathways. It is often used to investigate the role of integrins, which are cell surface receptors involved in cell-to-extracellular matrix interactions. This peptide sequence mimics parts of extracellular matrix proteins, making it useful in experiments to understand how cells attach, migrate, and communicate within tissues. Additionally, it is employed in the development of biomaterials and tissue engineering, where it can be incorporated into scaffolds to promote cell attachment and growth. Its role in modulating cellular behavior also makes it relevant in studies related to wound healing, cancer metastasis, and regenerative medicine.