This compound is used in biomedical research to study the function and signaling of the CXCR2 receptor, a G-protein-coupled receptor involved in inflammation and immune responses. It is expressed in HEK293 cells, which provides a stable and reproducible cellular system for screening potential drug candidates that modulate CXCR2 activity. It is commonly used in assays to evaluate ligand binding, chemotaxis, and intracellular signaling pathways such as calcium flux and ERK phosphorylation. Due to CXCR2's role in diseases like chronic obstructive pulmonary disease (COPD), cancer, and psoriasis, this cell-based system supports the development of therapeutic inhibitors targeting inflammatory and oncological conditions.