huCXCR4-HEK293,
Reagent
Code: #248491
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-80℃
description Product Description
This chemical is not a conventional small-molecule compound but rather a cell line—specifically, HEK293 cells engineered to stably express the human CXCR4 receptor. It is primarily used in biomedical research to study the function and signaling of the CXCR4 chemokine receptor, which plays key roles in immune cell trafficking, stem cell homing, cancer metastasis, and HIV infection. The cell line serves as a reliable model system for screening and characterizing potential drug candidates that target CXCR4, such as antagonists or inhibitors. It is widely used in assays involving calcium flux, chemotaxis, receptor internalization, and ligand binding. Due to its consistent receptor expression, it supports high-throughput drug discovery and mechanistic studies in oncology, immunology, and virology.
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