Superoxide dismutase (SOD) derived from human red blood cells is widely used in research and therapeutic applications due to its potent antioxidant properties. It is primarily employed to neutralize superoxide radicals, one of the main reactive oxygen species (ROS) involved in oxidative stress. This makes it valuable in studies related to inflammation, aging, and neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS). In cell culture and biochemical assays, this highly purified, salt-free form of SOD is used to protect enzymes and cells from oxidative damage, ensuring experimental accuracy and cell viability. Its human origin reduces the risk of immunogenic reactions, making it suitable for preclinical studies aiming at drug development and evaluation of oxidative pathways in human physiology. Due to its lyophilized, stable form, it is also used in formulation development for potential therapeutic products targeting ischemia-reperfusion injury, chronic inflammatory conditions, and other ROS-mediated disorders. Its high specific activity (≥2,500 units/mg protein) ensures efficient radical scavenging at low concentrations, enhancing its utility in sensitive applications.