Valpromide is primarily used as an anticonvulsant in the treatment of epilepsy, helping to control various types of seizures, including generalized and partial seizures. It is also employed in the management of bipolar disorder, particularly for stabilizing mood during manic episodes. Due to its ability to modulate brain activity, it may be used as a preventive treatment for migraine headaches. Valpromide acts as a prodrug in some cases, converting to valproic acid in the body, which enhances its therapeutic effect. Its use is often considered when other antiepileptic drugs are not well tolerated, offering an alternative with a potentially favorable side effect profile.